A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR
A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR
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Author / Creator
Song, Runjie , Ma, Shuoqian , Xu, Jiajia , Ren, Xin , Guo, Peilan , Liu, Huijiao , Li, Peng , Yin, Fan , Liu, Mei , Wang, Qiang , Yu, Lei , Liu, Jiali , Duan, Binwei , Rahman, Nafis A. , Wołczyński, Sławomir , Li, Guangming and Li, Xiangdong
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
hsa_circ_0001727 (circZKSCAN1) has been reported to be a tumor-associated circRNA by sponging microRNAs. Intriguingly, we found that circZKSCAN1 encoded a secretory peptide (circZKSaa) in the liver. The present study aims to elucidate the potential role and molecular mechanism of circZKSaa in the regulation of hepatocellular carcinoma (HCC) progres...
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Full title
A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR
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TN_cdi_doaj_primary_oai_doaj_org_article_3ab1af1678eb4701bbe2b0a5ceb2a0a1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ab1af1678eb4701bbe2b0a5ceb2a0a1
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-023-01719-9
