Imbalance between the function of Na+-K+-2Cl and K+-Cl impairs Cl– homeostasis in human focal cortic...
Imbalance between the function of Na+-K+-2Cl and K+-Cl impairs Cl– homeostasis in human focal cortical dysplasia
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Lausanne: Frontiers Research Foundation
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English
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Lausanne: Frontiers Research Foundation
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Objective: Altered expression patterns of Na+-K+-2Cl- (NKCC1) and K+-Cl- (KCC2) co-transporters have been implicated in the pathogenesis of epilepsy. Here, we assessed the effects of imbalanced NKCC1 and KCC2 on γ-aminobutyric acidergic (GABAergic) neurotransmission in certain brain regions involved in human focal cortical dysplasia (FCD). Methods:...
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Full title
Imbalance between the function of Na+-K+-2Cl and K+-Cl impairs Cl– homeostasis in human focal cortical dysplasia
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TN_cdi_doaj_primary_oai_doaj_org_article_3aca929bbb684b5696f68622c98802d1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3aca929bbb684b5696f68622c98802d1
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ISSN
1662-5099
E-ISSN
1662-5099
DOI
10.3389/fnmol.2022.954167
