Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using p...
Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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DNase-seq and ATAC-seq are broadly used methods to assay open chromatin regions genome-wide. The single nucleotide resolution of DNase-seq has been further exploited to infer transcription factor binding sites (TFBSs) in regulatory regions through footprinting. Recent studies have demonstrated the sequence bias of DNase I and its adverse effects on...
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Reproducible inference of transcription factor footprints in ATAC-seq and DNase-seq datasets using protocol-specific bias modeling
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TN_cdi_doaj_primary_oai_doaj_org_article_3ae2ff152f1843789e06a3b2bcd88e33
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ae2ff152f1843789e06a3b2bcd88e33
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-019-1654-y
