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CRISPR technologies and the search for the PAM-free nuclease

CRISPR technologies and the search for the PAM-free nuclease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b0005fc19784851be7b5e4a5d35393a

CRISPR technologies and the search for the PAM-free nuclease

About this item

Full title

CRISPR technologies and the search for the PAM-free nuclease

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-01, Vol.12 (1), p.555-555, Article 555

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The ever-expanding set of CRISPR technologies and their programmable RNA-guided nucleases exhibit remarkable flexibility in DNA targeting. However, this flexibility comes with an ever-present constraint: the requirement for a protospacer adjacent motif (PAM) flanking each target. While PAMs play an essential role in self/nonself discrimination by C...

Alternative Titles

Full title

CRISPR technologies and the search for the PAM-free nuclease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3b0005fc19784851be7b5e4a5d35393a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b0005fc19784851be7b5e4a5d35393a

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-020-20633-y

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