Tankyrases as modulators of pro-tumoral functions: molecular insights and therapeutic opportunities
Tankyrases as modulators of pro-tumoral functions: molecular insights and therapeutic opportunities
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Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Tankyrase 1 (TNKS1) and tankyrase 2 (TNKS2) are two homologous proteins that are gaining increasing importance due to their implication in multiple pathways and diseases such as cancer. TNKS1/2 interact with a large variety of substrates through the ankyrin (ANK) domain, which recognizes a sequence present in all the substrates of tankyrase, called...
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Tankyrases as modulators of pro-tumoral functions: molecular insights and therapeutic opportunities
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TN_cdi_doaj_primary_oai_doaj_org_article_3b1e510960404a79bb244905483cb9ff
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b1e510960404a79bb244905483cb9ff
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ISSN
1756-9966,0392-9078
E-ISSN
1756-9966
DOI
10.1186/s13046-021-01950-6
