Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tu...
Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression
About this item
Full title
Author / Creator
Comba, Andrea , Faisal, Syed M. , Dunn, Patrick J. , Argento, Anna E. , Hollon, Todd C. , Al-Holou, Wajd N. , Varela, Maria Luisa , Zamler, Daniel B. , Quass, Gunnar L. , Apostolides, Pierre F. , Abel, Clifford , Brown, Christine E. , Kish, Phillip E. , Kahana, Alon , Kleer, Celina G. , Motsch, Sebastien , Castro, Maria G. and Lowenstein, Pedro R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Intra-tumoral heterogeneity is a hallmark of glioblastoma that challenges treatment efficacy. However, the mechanisms that set up tumor heterogeneity and tumor cell migration remain poorly understood. Herein, we present a comprehensive spatiotemporal study that aligns distinctive intra-tumoral histopathological structures, oncostreams, with dynamic...
Alternative Titles
Full title
Spatiotemporal analysis of glioma heterogeneity reveals COL1A1 as an actionable target to disrupt tumor progression
Authors, Artists and Contributors
Author / Creator
Faisal, Syed M.
Dunn, Patrick J.
Argento, Anna E.
Hollon, Todd C.
Al-Holou, Wajd N.
Varela, Maria Luisa
Zamler, Daniel B.
Quass, Gunnar L.
Apostolides, Pierre F.
Abel, Clifford
Brown, Christine E.
Kish, Phillip E.
Kahana, Alon
Kleer, Celina G.
Motsch, Sebastien
Castro, Maria G.
Lowenstein, Pedro R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3b351a9de1174a41bae1168e3664c972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b351a9de1174a41bae1168e3664c972
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-31340-1
