MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The role of mitochondria dynamics and its molecular regulators remains largely unknown during naïve-to-primed pluripotent cell interconversion. Here we report that mitochondrial MTCH2 is a regulator of mitochondrial fusion, essential for the naïve-to-primed interconversion of murine embryonic stem cells (ESCs). During this interconversion, wild-typ...
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MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells
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TN_cdi_doaj_primary_oai_doaj_org_article_3b42662e2cea47e7be6870e3d559ad27
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b42662e2cea47e7be6870e3d559ad27
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-07519-w
