Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide...
Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Revealing the gene targets of distal regulatory elements is challenging yet critical for interpreting regulome data. Experiment-derived enhancer-gene links are restricted to a small set of enhancers and/or cell types, while the accuracy of genome-wide approaches remains elusive due to the lack of a systematic evaluation. We combined multiple spatia...
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Comprehensive enhancer-target gene assignments improve gene set level interpretation of genome-wide regulatory data
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TN_cdi_doaj_primary_oai_doaj_org_article_3b4ff7a18c63408e970ba0ae1b45ae0f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b4ff7a18c63408e970ba0ae1b45ae0f
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-022-02668-0
