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Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages

Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b5947ff6cbd4432a53afe89c0e9d0eb

Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages

About this item

Full title

Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2025-01, Vol.30 (1), p.123

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Inosine (IS) is a naturally occurring metabolite of adenosine with potent immunomodulatory effects. This study investigates the immunomodulatory effects of inosine, particularly its ability to inhibit the development of colorectal cancer (CRC) cells CT26 through modulation of macrophage phenotypes. Aside from the already reported effects of inosine...

Alternative Titles

Full title

Inosine Prevents Colorectal Cancer Progression by Inducing M1 Phenotypic Polarization of Macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3b5947ff6cbd4432a53afe89c0e9d0eb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b5947ff6cbd4432a53afe89c0e9d0eb

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules30010123

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