Molecular basis for azetidine-2-carboxylic acid biosynthesis
Molecular basis for azetidine-2-carboxylic acid biosynthesis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Azetidine-2-carboxylic acid (AZE) is a long-known plant metabolite. Recently, AZE synthases have been identified in bacterial natural product pathways involving non-ribosomal peptide synthetases. AZE synthases catalyse the intramolecular 4-exo-tet cyclisation of
S
-adenosylmethionine (SAM), yielding a highly strained heterocycle. Here, we com...
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Molecular basis for azetidine-2-carboxylic acid biosynthesis
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TN_cdi_doaj_primary_oai_doaj_org_article_3b64b03c564f48c998709093aad73212
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b64b03c564f48c998709093aad73212
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-025-56610-6
