Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent...
Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells
About this item
Full title
Author / Creator
Stillitano, Francesca , Hansen, Jens , Kong, Chi-Wing , Karakikes, Ioannis , Funck-Brentano, Christian , Geng, Lin , Scott, Stuart , Reynier, Stephan , Wu, Ma , Valogne, Yannick , Desseaux, Carole , Salem, Joe-Elie , Jeziorowska, Dorota , Zahr, Noël , Li, Ronald , Iyengar, Ravi , Hajjar, Roger J and Hulot, Jean-Sébastien
Publisher
England: eLife Sciences Publications Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Sciences Publications Ltd
Subjects
More information
Scope and Contents
Contents
A large number of drugs can induce prolongation of cardiac repolarization and life-threatening cardiac arrhythmias. The prediction of this side effect is however challenging as it usually develops in some genetically predisposed individuals with normal cardiac repolarization at baseline. Here, we describe a platform based on a genetically diverse p...
Alternative Titles
Full title
Modeling susceptibility to drug-induced long QT with a panel of subject-specific induced pluripotent stem cells
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3b878456b2a444ebbdf9d3342f144ebc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b878456b2a444ebbdf9d3342f144ebc
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.19406
