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UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b8ac826e8224f39920b2d2a0010217a

UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

About this item

Full title

UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2021-04, Vol.10

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

To adapt in an ever-changing environment, cells must integrate physical and chemical signals and translate them into biological meaningful information through complex signaling pathways. By combining lipidomic and proteomic approaches with functional analysis, we have shown that ubiquitin domain-containing protein 1 (UBTD1) plays a crucial role in...

Alternative Titles

Full title

UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3b8ac826e8224f39920b2d2a0010217a

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b8ac826e8224f39920b2d2a0010217a

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.68348