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Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b8ffa6689c34fa3a6cde5b04740c305

Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

About this item

Full title

Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

Publisher

United States: American Chemical Society

Journal title

ACS central science, 2024-08, Vol.10 (8), p.1640-1656

Language

English

Formats

Publication information

Publisher

United States: American Chemical Society

More information

Scope and Contents

Contents

Glioblastoma (GBM) is the most aggressive and frequently occurring type of malignant brain tumor in adults. The initiation, progression, and recurrence of malignant tumors are known to be driven by a small subpopulation of cells known as tumor-initiating cells or cancer stem cells (CSCs). GBM CSCs play a pivotal role in orchestrating drug resistanc...

Alternative Titles

Full title

Identification of Rocaglate Acyl Sulfamides as Selective Inhibitors of Glioblastoma Stem Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3b8ffa6689c34fa3a6cde5b04740c305

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b8ffa6689c34fa3a6cde5b04740c305

Other Identifiers

ISSN

2374-7943

E-ISSN

2374-7951

DOI

10.1021/acscentsci.4c01073

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