Simple gene signature to assess murine fibroblast polarization
Simple gene signature to assess murine fibroblast polarization
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Author / Creator
Ledoult, Emmanuel , Jendoubi, Manel , Collet, Aurore , Guerrier, Thomas , Largy, Alexis , Speca, Silvia , Vivier, Solange , Bray, Fabrice , Figeac, Martin , Hachulla, Eric , Labalette, Myriam , Leprêtre, Frédéric , Sebda, Shéhérazade , Sanges, Sébastien , Rolando, Christian , Sobanski, Vincent , Dubucquoi, Sylvain and Launay, David
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
We provide an original multi-stage approach identifying a gene signature to assess murine fibroblast polarization. Prototypic polarizations (inflammatory/fibrotic) were induced by seeded mouse embryonic fibroblasts (MEFs) with TNFα or TGFß1, respectively. The transcriptomic and proteomic profiles were obtained by RNA microarray and LC-MS/MS. Gene O...
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Full title
Simple gene signature to assess murine fibroblast polarization
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TN_cdi_doaj_primary_oai_doaj_org_article_3b929e9e55f1469f8ebd0f605909aaa3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3b929e9e55f1469f8ebd0f605909aaa3
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-15640-6