Neoantigen vaccine: an emerging tumor immunotherapy
Neoantigen vaccine: an emerging tumor immunotherapy
About this item
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Author / Creator
Peng, Miao , Mo, Yongzhen , Wang, Yian , Wu, Pan , Zhang, Yijie , Xiong, Fang , Guo, Can , Wu, Xu , Li, Yong , Li, Xiaoling , Li, Guiyuan , Xiong, Wei and Zeng, Zhaoyang
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Genetic instability of tumor cells often leads to the occurrence of a large number of mutations, and expression of non-synonymous mutations can produce tumor-specific antigens called neoantigens. Neoantigens are highly immunogenic as they are not expressed in normal tissues. They can activate CD4+ and CD8+ T cells to generate immune response and ha...
Alternative Titles
Full title
Neoantigen vaccine: an emerging tumor immunotherapy
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3bb25d56ea0440378e7af782d27f8503
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3bb25d56ea0440378e7af782d27f8503
Other Identifiers
ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/s12943-019-1055-6
