Multi-omics analysis of human mesenchymal stem cells shows cell aging that alters immunomodulatory a...
Multi-omics analysis of human mesenchymal stem cells shows cell aging that alters immunomodulatory activity through the downregulation of PD-L1
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Author / Creator
Gao, Yuchen , Chi, Ying , Chen, Yunfei , Wang, Wentian , Li, Huiyuan , Zheng, Wenting , Zhu, Ping , An, Jinying , Duan, Yanan , Sun, Ting , Liu, Xiaofan , Xue, Feng , Liu, Wei , Fu, Rongfeng , Han, Zhibo , Zhang, Yingchi , Yang, Renchi , Cheng, Tao , Wei, Jun , Zhang, Lei and Zhang, Xiaomin
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Mesenchymal stem cells (MSCs) possess potent immunomodulatory activity and have been extensively investigated for their therapeutic potential in treating inflammatory disorders. However, the mechanisms underlying the immunosuppressive function of MSCs are not fully understood, hindering the development of standardized MSC-based therapies for clinic...
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Full title
Multi-omics analysis of human mesenchymal stem cells shows cell aging that alters immunomodulatory activity through the downregulation of PD-L1
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TN_cdi_doaj_primary_oai_doaj_org_article_3bc172cc2e194b8b89c4aefdeb61c25d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3bc172cc2e194b8b89c4aefdeb61c25d
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-39958-5
