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Studies on the anticonvulsant activity and influence on GABA-ergic neurotransmission of 1,2,4-triazo...

Studies on the anticonvulsant activity and influence on GABA-ergic neurotransmission of 1,2,4-triazo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3bc996d0bbf54916b37f0d7a6cd864e5

Studies on the anticonvulsant activity and influence on GABA-ergic neurotransmission of 1,2,4-triazole-3-thione- based compounds

About this item

Full title

Studies on the anticonvulsant activity and influence on GABA-ergic neurotransmission of 1,2,4-triazole-3-thione- based compounds

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2014-07, Vol.19 (8), p.11279-11299

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The anticonvulsant activity of several 1,2,4-triazole-3-thione derivatives on mouse maximal electroshock-induced seizures was tested in this study. Characteristic features of all active compounds were rapid onset of action and long lasting effect. Structure-activity observations showed that the probability of obtaining compounds exerting anticonvul...

Alternative Titles

Full title

Studies on the anticonvulsant activity and influence on GABA-ergic neurotransmission of 1,2,4-triazole-3-thione- based compounds

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3bc996d0bbf54916b37f0d7a6cd864e5

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3bc996d0bbf54916b37f0d7a6cd864e5

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules190811279

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