Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma prog...
Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chromosomal instability (CIN) and epigenetic alterations have been implicated in tumor progression and metastasis; yet how these two hallmarks of cancer are related remains poorly understood. By integrating genetic, epigenetic, and functional analyses at the single cell level, we show that progression of uveal melanoma (UM), the most common intraoc...
Alternative Titles
Full title
Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3bfb2543650b4dffa2fb1404ab14b57d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3bfb2543650b4dffa2fb1404ab14b57d
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-25529-z
