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Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3c1c97f9f96f44b8b385caffd639b374

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

About this item

Full title

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2017-07, Vol.8 (1), p.15965-15, Article 15965

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Pancreatic ductal adenocarcinoma is a notoriously difficult-to-treat cancer and patients are in need of novel therapies. We have shown previously that these tumours have altered metabolic requirements, making them highly reliant on a number of adaptations including a non-canonical glutamine (Gln) metabolic pathway and that inhibition of downstream...

Alternative Titles

Full title

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3c1c97f9f96f44b8b385caffd639b374

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3c1c97f9f96f44b8b385caffd639b374

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms15965

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