Inhibition of CCl4-induced liver inflammation and fibrosis by a NEU3 inhibitor
Inhibition of CCl4-induced liver inflammation and fibrosis by a NEU3 inhibitor
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Sialic acids are located on the ends of many glycoconjugates and are cleaved off by enzymes called sialidases (neuraminidases). Upregulation of neuraminidase 3 (NEU3) is associated with intestinal inflammation and colitis, neuroinflammation, and lung fibrosis. Genetic ablation of NEU3 or pharmacological inhibition of NEU3 reduces lung fibrosis in m...
Alternative Titles
Full title
Inhibition of CCl4-induced liver inflammation and fibrosis by a NEU3 inhibitor
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3c29cc122d5f4693b1f9fcc30f202fa7
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3c29cc122d5f4693b1f9fcc30f202fa7
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0308060
