Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled...
Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Background
Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have been applied in clinical pretargeting studies; unfortunately, these systems led to immunogenic responses in p...
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Full title
Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging
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TN_cdi_doaj_primary_oai_doaj_org_article_3c3a2b2c7f3b4c0690ccc0893c5a719d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3c3a2b2c7f3b4c0690ccc0893c5a719d
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ISSN
2191-219X
E-ISSN
2191-219X
DOI
10.1186/s13550-019-0520-y
