Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis in juvenile bone
Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis in juvenile bone
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Skeletal development depends on coordinated angiogenesis and osteogenesis. Bone morphogenetic proteins direct bone formation in part by activating SMAD1/5 signaling in osteoblasts. However, the role of SMAD1/5 in skeletal endothelium is unknown. Here, we found that endothelial cell-conditional SMAD1/5 depletion in juvenile mice caused metaphyseal a...
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Full title
Endothelial SMAD1/5 signaling couples angiogenesis to osteogenesis in juvenile bone
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TN_cdi_doaj_primary_oai_doaj_org_article_3c3f2b0dd6834e6782d3048a6c987169
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3c3f2b0dd6834e6782d3048a6c987169
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ISSN
2399-3642
E-ISSN
2399-3642
DOI
10.1038/s42003-024-05915-1
