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PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3cd9593b5a3c449085e3011eabf08516

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

B-cell lymphoma (BCL) is the most common hematologic malignancy. While sequencing studies gave insights into BCL genetics, identification of non-mutated cancer genes remains challenging. Here, we describe
PiggyBac
transposon tools and mouse models for recessive screening and show their application to study clonal B-cell lymphomagenesis. In a...

Alternative Titles

Full title

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3cd9593b5a3c449085e3011eabf08516

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3cd9593b5a3c449085e3011eabf08516

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-09180-3

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