Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem6...
Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage
About this item
Full title
Author / Creator
Schulz, Angela , Müller, Nicola Victoria , van de Lest, Nina Anne , Eisenreich, Andreas , Schmidbauer, Martina , Barysenka, Andrei , Purfürst, Bettina , Sporbert, Anje , Lorenzen, Theodor , Meyer, Alexander M , Herlan, Laura , Witten, Anika , Rühle, Frank , Zhou, Weibin , de Heer, Emile , Scharpfenecker, Marion , Panáková, Daniela , Stoll, Monika and Kreutz, Reinhold
Publisher
England: eLife Science Publications, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: eLife Science Publications, Ltd
Subjects
More information
Scope and Contents
Contents
Unraveling the genetic susceptibility of complex diseases such as chronic kidney disease remains challenging. Here, we used inbred rat models of kidney damage associated with elevated blood pressure for the comprehensive analysis of a major albuminuria susceptibility locus detected in these models. We characterized its genomic architecture by conge...
Alternative Titles
Full title
Analysis of the genomic architecture of a complex trait locus in hypertensive rat models links Tmem63c to kidney damage
Authors, Artists and Contributors
Author / Creator
Müller, Nicola Victoria
van de Lest, Nina Anne
Eisenreich, Andreas
Schmidbauer, Martina
Barysenka, Andrei
Purfürst, Bettina
Sporbert, Anje
Lorenzen, Theodor
Meyer, Alexander M
Herlan, Laura
Witten, Anika
Rühle, Frank
Zhou, Weibin
de Heer, Emile
Scharpfenecker, Marion
Panáková, Daniela
Stoll, Monika
Kreutz, Reinhold
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3ce65e8761e146108e0f630955c54002
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ce65e8761e146108e0f630955c54002
Other Identifiers
ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.42068
