1114 Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robus...
1114 Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models
About this item
Full title
Author / Creator
Publisher
London: BMJ Publishing Group Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group Ltd
Subjects
More information
Scope and Contents
Contents
BackgroundSTING is an innate immune pathway that detects intracellular DNA from foreign pathogens as well as stressed or tumor cells and activates a proinflammatory, type I interferon (IFN) response.1 STING activation is critical for mounting anti-viral immunity, and recent advances suggest this pathway can be co-opted to drive an anti-tumor immune...
Alternative Titles
Full title
1114 Targeted delivery of a potent STING agonist payload via an antibody drug conjugate drives robust antitumor activity in preclinical models
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3d10db68c1aa4ab699f45680ebe496a8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d10db68c1aa4ab699f45680ebe496a8
Other Identifiers
E-ISSN
2051-1426
DOI
10.1136/jitc-2023-SITC2023.1114
