Epigenetic OCT4 regulatory network: stochastic analysis of cellular reprogramming
Epigenetic OCT4 regulatory network: stochastic analysis of cellular reprogramming
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Experimental studies have shown that chromatin modifiers have a critical effect on cellular reprogramming, i.e., the conversion of differentiated cells to pluripotent stem cells. Here, we develop a model of the OCT4 gene regulatory network that includes genes expressing chromatin modifiers TET1 and JMJD2, and the chromatin modification circuit on w...
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Epigenetic OCT4 regulatory network: stochastic analysis of cellular reprogramming
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TN_cdi_doaj_primary_oai_doaj_org_article_3d4040b1f4a8481e9d59ac4d130e8d51
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d4040b1f4a8481e9d59ac4d130e8d51
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2056-7189
E-ISSN
2056-7189
DOI
10.1038/s41540-023-00326-0