A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus vari...
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge
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Author / Creator
Wuertz, Kathryn McGuckin , Barkei, Erica K. , Chen, Wei-Hung , Martinez, Elizabeth J. , Lakhal-Naouar, Ines , Jagodzinski, Linda L. , Paquin-Proulx, Dominic , Gromowski, Gregory D. , Swafford, Isabella , Ganesh, Akshaya , Dong, Ming , Zeng, Xiankun , Thomas, Paul V. , Sankhala, Rajeshwer S. , Hajduczki, Agnes , Peterson, Caroline E. , Kuklis, Caitlin , Soman, Sandrine , Wieczorek, Lindsay , Zemil, Michelle , Anderson, Alexander , Darden, Janice , Hernandez, Heather , Grove, Hannah , Dussupt, Vincent , Hack, Holly , de la Barrera, Rafael , Zarling, Stasya , Wood, James F. , Froude, Jeffrey W. , Gagne, Matthew , Henry, Amy R. , Mokhtari, Elham Bayat , Mudvari, Prakriti , Krebs, Shelly J. , Pekosz, Andrew S. , Currier, Jeffrey R. , Kar, Swagata , Porto, Maciel , Winn, Adrienne , Radzyminski, Kamil , Lewis, Mark G. , Vasan, Sandhya , Suthar, Mehul , Polonis, Victoria R. , Matyas, Gary R. , Boritz, Eli A. , Douek, Daniel C. , Seder, Robert A. , Daye, Sharon P. , Rao, Mangala , Peel, Sheila A. , Joyce, M. Gordon , Bolton, Diane L. , Michael, Nelson L. and Modjarrad, Kayvon
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
The emergence of SARS-CoV-2 variants of concern (VOC) requires adequate coverage of vaccine protection. We evaluated whether a SARS-CoV-2 spike ferritin nanoparticle vaccine (SpFN), adjuvanted with the Army Liposomal Formulation QS21 (ALFQ), conferred protection against the Alpha (B.1.1.7), and Beta (B.1.351) VOCs in Syrian golden hamsters. SpFN-AL...
Alternative Titles
Full title
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge
Authors, Artists and Contributors
Author / Creator
Barkei, Erica K.
Chen, Wei-Hung
Martinez, Elizabeth J.
Lakhal-Naouar, Ines
Jagodzinski, Linda L.
Paquin-Proulx, Dominic
Gromowski, Gregory D.
Swafford, Isabella
Ganesh, Akshaya
Dong, Ming
Zeng, Xiankun
Thomas, Paul V.
Sankhala, Rajeshwer S.
Hajduczki, Agnes
Peterson, Caroline E.
Kuklis, Caitlin
Soman, Sandrine
Wieczorek, Lindsay
Zemil, Michelle
Anderson, Alexander
Darden, Janice
Hernandez, Heather
Grove, Hannah
Dussupt, Vincent
Hack, Holly
de la Barrera, Rafael
Zarling, Stasya
Wood, James F.
Froude, Jeffrey W.
Gagne, Matthew
Henry, Amy R.
Mokhtari, Elham Bayat
Mudvari, Prakriti
Krebs, Shelly J.
Pekosz, Andrew S.
Currier, Jeffrey R.
Kar, Swagata
Porto, Maciel
Winn, Adrienne
Radzyminski, Kamil
Lewis, Mark G.
Vasan, Sandhya
Suthar, Mehul
Polonis, Victoria R.
Matyas, Gary R.
Boritz, Eli A.
Douek, Daniel C.
Seder, Robert A.
Daye, Sharon P.
Rao, Mangala
Peel, Sheila A.
Joyce, M. Gordon
Bolton, Diane L.
Michael, Nelson L.
Modjarrad, Kayvon
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3d4762c8ae9d4d3e8004ffeb07a8b88e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d4762c8ae9d4d3e8004ffeb07a8b88e
Other Identifiers
ISSN
2059-0105
E-ISSN
2059-0105
DOI
10.1038/s41541-021-00392-7