Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis
Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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This study aimed to investigate the role of src-homology protein tyrosine phosphatase-1 (SHP-1)–signal transducer and activator of transcription 3 (STAT3) pathway in liver fibrogenesis and the anti-fibrotic effect of SHP-1 agonist. The antifibrotic activity of SC-43, a sorafenib derivative with an enhanced SHP-1 activity, was evaluated in two fibro...
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Full title
Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis
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TN_cdi_doaj_primary_oai_doaj_org_article_3d50e6bc0e2648bebc05dad65df544e8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d50e6bc0e2648bebc05dad65df544e8
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-01572-z
