Dupilumab aggravates Sézary syndrome: The importance of accurate pathological diagnosis
Dupilumab aggravates Sézary syndrome: The importance of accurate pathological diagnosis
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Tokyo: Frontiers Media SA
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English
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Tokyo: Frontiers Media SA
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Monoclonal gene rearrangement of T-cell receptor β-chain was identified in her PB by Southern blot analysis. When dupilumab blocks IL-4 and IL-13 receptors, serum IL-13 levels increase. Because dupilumab inhibits IL-13Rα1 but not IL-13Rα2 signaling, increased IL-13 levels due to dupilumab stimulate IL-13Rα2, leading to the activation and proliferat...
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Full title
Dupilumab aggravates Sézary syndrome: The importance of accurate pathological diagnosis
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TN_cdi_doaj_primary_oai_doaj_org_article_3d78f5e798664d97bd2d4b4b20ea7bd3
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3d78f5e798664d97bd2d4b4b20ea7bd3
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ISSN
2574-4593
E-ISSN
2574-4593
DOI
10.1002/cia2.12311
