Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African...
Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children (SchistoSAM): protocol of a proof-of-concept, open-label, two-arm, individually-randomised controlled trial
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Roucher, Clémentine , Brosius, Isabel , Mbow, Moustapha , Faye, Babacar Thiendella , De Hondt, Annelies , Smekens, Bart , Arango, Diana , Burm, Christophe , Tsoumanis, Achilleas , Paredis, Linda , van Herrewege, Yven , Potters, Idzi , Cisse, Badara , Mboup, Souleymane , Polman, Katja and Bottieau, Emmanuel
Publisher
England: British Medical Journal Publishing Group
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Language
English
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England: British Medical Journal Publishing Group
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IntroductionAlternative drugs and diagnostics are needed for the treatment and control of schistosomiasis. The exclusive use of praziquantel (PZQ) in mass drug administration programmes may result in the emergence of drug resistance. PZQ has little activity against Schistosoma larvae, thus reinfection remains a problem in high-risk communities. Fur...
Alternative Titles
Full title
Evaluation of Artesunate-mefloquine as a Novel Alternative Treatment for Schistosomiasis in African Children (SchistoSAM): protocol of a proof-of-concept, open-label, two-arm, individually-randomised controlled trial
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TN_cdi_doaj_primary_oai_doaj_org_article_3da4c2cc84e141b5b33081c8df3a5e81
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3da4c2cc84e141b5b33081c8df3a5e81
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ISSN
2044-6055
E-ISSN
2044-6055
DOI
10.1136/bmjopen-2020-047147
