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Wnt pathway activation by ADP-ribosylation

Wnt pathway activation by ADP-ribosylation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3da63aa64149454db576577367439463

Wnt pathway activation by ADP-ribosylation

About this item

Full title

Wnt pathway activation by ADP-ribosylation

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2016-05, Vol.7 (1), p.11430-14, Article 11430

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Wnt/β-catenin signalling directs fundamental processes during metazoan development and can be aberrantly activated in cancer. Wnt stimulation induces the recruitment of the scaffold protein Axin from an inhibitory destruction complex to a stimulatory signalosome. Here we analyse the early effects of Wnt on Axin and find that the ADP-ribose polymera...

Alternative Titles

Full title

Wnt pathway activation by ADP-ribosylation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3da63aa64149454db576577367439463

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3da63aa64149454db576577367439463

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms11430

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