Profiling of driver mutations in lung adenocarcinoma patients identifies rare compound EGFR mutation...
Profiling of driver mutations in lung adenocarcinoma patients identifies rare compound EGFR mutations sensitive to second-generation EGFR-TKIs
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Author / Creator
Li, Jun , Zhang, Cuiyun , Guan, Yuping , Wang, Siyu , Zheng, Jiawen , Feng, Junnan , Han, Sile , Ma, Ruijuan , Ren, Pengfei , Li, Shasha , Groen, Harry J. M. , Kok, Klaas , van den Berg, Anke , Wei, Bing , Ma, Jie , Li, Hongle and Guo, Yongjun
Publisher
Singapore: Springer Nature Singapore
Journal title
Language
English
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Publication information
Publisher
Singapore: Springer Nature Singapore
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Contents
Background
Lung adenocarcinoma (LUAD) is the most predominant histological subtype of lung cancer characterized by driver mutations detected in a substantial proportion of the cases. Tyrosine kinase inhibitors (TKIs) are standard care for the patients with these mutations. In this study, we evaluated the efficiency of an NGS-based 8-gene test in...
Alternative Titles
Full title
Profiling of driver mutations in lung adenocarcinoma patients identifies rare compound EGFR mutations sensitive to second-generation EGFR-TKIs
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3dc4e66898d84391b36cf24c6a64f6d8
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3dc4e66898d84391b36cf24c6a64f6d8
Other Identifiers
ISSN
2731-4529
E-ISSN
2731-4529
DOI
10.1007/s44178-024-00139-z
