Implantation of biomimetic polydopamine nanocomposite scaffold promotes optic nerve regeneration thr...
Implantation of biomimetic polydopamine nanocomposite scaffold promotes optic nerve regeneration through modulating inhibitory microenvironment
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Author / Creator
Pan, Tonghe , Huang, Yate , Wei, Jinfei , Lai, Chen , Chen, Yangjun , Nan, Kaihui and Wu, Wencan
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Optic nerve regeneration remains challenging worldwide due to the limited intrinsic regenerative capacity of retinal ganglion cells (RGCs) and the inhibitory microenvironment. Oxidative stress, induced by excessive reactive oxygen species (ROS) following optic nerve injury, is associated with prolonged neuroinflammation, resulting in a secondary in...
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Full title
Implantation of biomimetic polydopamine nanocomposite scaffold promotes optic nerve regeneration through modulating inhibitory microenvironment
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TN_cdi_doaj_primary_oai_doaj_org_article_3dcf9e6222b6489aafb30cdb4e5e41e5
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3dcf9e6222b6489aafb30cdb4e5e41e5
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ISSN
1477-3155
E-ISSN
1477-3155
DOI
10.1186/s12951-024-02962-y