A novel strategy for site selective spin-labeling to investigate bioactive entities by DNP and EPR s...
A novel strategy for site selective spin-labeling to investigate bioactive entities by DNP and EPR spectroscopy
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
A novel specific spin-labeling strategy for bioactive molecules is presented for eptifibatide (integrilin) an antiplatelet aggregation inhibitor, which derives from the venom of certain rattlesnakes. By specifically labeling the disulfide bridge this molecule becomes accessible for analytical techniques such as Electron Paramagnetic Resonance (EPR)...
Alternative Titles
Full title
A novel strategy for site selective spin-labeling to investigate bioactive entities by DNP and EPR spectroscopy
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3e3cc9a70aab41148a91c6390f29b657
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e3cc9a70aab41148a91c6390f29b657
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-92975-6
