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Impact of T cell characteristics on CAR-T cell therapy in hematological malignancies

Impact of T cell characteristics on CAR-T cell therapy in hematological malignancies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e3d19d829fc46a7bb5eefac35652935

Impact of T cell characteristics on CAR-T cell therapy in hematological malignancies

About this item

Full title

Impact of T cell characteristics on CAR-T cell therapy in hematological malignancies

Publisher

London: Nature Publishing Group UK

Journal title

Blood cancer journal (New York), 2024-12, Vol.14 (1), p.213-10, Article 213

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Chimeric antigen receptor (CAR) T-cell therapy has revolutionized the treatment paradigms for hematological malignancies. However, more than half of these patients cannot achieve sustainable tumor control, partially due to the inadequate potency of CAR-T cells in eradicating tumor cells. T cells are crucial components of the anti-tumor immune respo...

Alternative Titles

Full title

Impact of T cell characteristics on CAR-T cell therapy in hematological malignancies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3e3d19d829fc46a7bb5eefac35652935

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e3d19d829fc46a7bb5eefac35652935

Other Identifiers

ISSN

2044-5385

E-ISSN

2044-5385

DOI

10.1038/s41408-024-01193-6

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