Impact of T cell characteristics on CAR-T cell therapy in hematological malignancies
Impact of T cell characteristics on CAR-T cell therapy in hematological malignancies
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Chimeric antigen receptor (CAR) T-cell therapy has revolutionized the treatment paradigms for hematological malignancies. However, more than half of these patients cannot achieve sustainable tumor control, partially due to the inadequate potency of CAR-T cells in eradicating tumor cells. T cells are crucial components of the anti-tumor immune respo...
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Impact of T cell characteristics on CAR-T cell therapy in hematological malignancies
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TN_cdi_doaj_primary_oai_doaj_org_article_3e3d19d829fc46a7bb5eefac35652935
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e3d19d829fc46a7bb5eefac35652935
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ISSN
2044-5385
E-ISSN
2044-5385
DOI
10.1038/s41408-024-01193-6