Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth fac...
Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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We had previously demonstrated overexpression of fibroblast growth factor receptor-4 (FGFR4) in hepatocellular carcinoma (HCC). However, additional molecular mechanisms resulting in amplified FGFR4 signaling in HCC remain under-studied. Here, we studied the mechanistic role of its co-receptor klotho-beta (KLB) in driving elevated FGFR4 activity in...
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Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma
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TN_cdi_doaj_primary_oai_doaj_org_article_3e3f706e1dfa4b8a93a5ff9db332dbb8
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e3f706e1dfa4b8a93a5ff9db332dbb8
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ISSN
1476-4598
E-ISSN
1476-4598
DOI
10.1186/1476-4598-11-14
