Treatment with oncolytic vaccinia virus infects tumor-infiltrating regulatory and exhausted T cells
Treatment with oncolytic vaccinia virus infects tumor-infiltrating regulatory and exhausted T cells
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England: BMJ Publishing Group Ltd
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Language
English
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England: BMJ Publishing Group Ltd
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BackgroundOncolytic viruses (OVs) are an attractive way to increase immune infiltration into an otherwise cold tumor. While OVs are engineered to selectively infect tumor cells, there is evidence that they can infect other non-malignant cells in the tumor. We sought to determine if oncolytic vaccinia virus (VV) can infect lymphocytes in the tumor a...
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Full title
Treatment with oncolytic vaccinia virus infects tumor-infiltrating regulatory and exhausted T cells
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TN_cdi_doaj_primary_oai_doaj_org_article_3e5dce664fb64004b4339f0027efe502
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e5dce664fb64004b4339f0027efe502
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ISSN
2051-1426
E-ISSN
2051-1426
DOI
10.1136/jitc-2024-009062
