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MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions

MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e983790f4d740f6875bec76ced943af

MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions

About this item

Full title

MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2024-11, Vol.15 (11), p.851-10, Article 851

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mixed lineage kinase domain-like (MLKL) is a pseudokinase, best known for its role as the terminal effector of the necroptotic cell death pathway. MLKL-mediated necroptosis has long been linked to various age-related pathologies including neurodegeneration, atherosclerosis and male reproductive decline, however many of these attributions remain con...

Alternative Titles

Full title

MLKL deficiency elevates testosterone production in male mice independently of necroptotic functions

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3e983790f4d740f6875bec76ced943af

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3e983790f4d740f6875bec76ced943af

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-024-07242-z

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