Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction
Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Microglia are highly motile glial cells that are proposed to mediate synaptic pruning during neuronal circuit formation. Disruption of signaling between microglia and neurons leads to an excess of immature synaptic connections, thought to be the result of impaired phagocytosis of synapses by microglia. However, until now the direct phagocytosis of...
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Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction
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TN_cdi_doaj_primary_oai_doaj_org_article_3ebaa88953d7458785bcccb29c6b1bc7
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ebaa88953d7458785bcccb29c6b1bc7
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-018-03566-5
