Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nan...
Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Effective treatments of neurodegenerative diseases require drugs to be actively transported across the blood-brain barrier (BBB). However, nanoparticle drug carriers explored for this purpose show negligible brain uptake, and the lack of basic understanding of nanoparticle-BBB interactions underlies many translational failures. Here, using two-phot...
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Full title
Post-capillary venules are the key locus for transcytosis-mediated brain delivery of therapeutic nanoparticles
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TN_cdi_doaj_primary_oai_doaj_org_article_3ecb3577f7e2486e85315477978e25ca
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ecb3577f7e2486e85315477978e25ca
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-021-24323-1
