Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation...
Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Heme oxygenase-1 (HO-1) is a critical cytoprotective enzyme that limits oxidative stress, inflammation, and cellular injury within the central nervous system (CNS) and other tissues. We previously demonstrated that HO-1 protein expression is decreased within the brains of HIV+ subjects and that this HO-1 reduction correlates with CNS immune activat...
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Full title
Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection
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TN_cdi_doaj_primary_oai_doaj_org_article_3ed07909158f4308ae1f4f340a501655
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ed07909158f4308ae1f4f340a501655
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ISSN
1742-2094
E-ISSN
1742-2094
DOI
10.1186/s12974-018-1102-z
