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A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ed28a4885534b4f9dbe3db52b4d222c

A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

About this item

Full title

A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2019-11, Vol.10 (1), p.5404-13, Article 5404

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Glycosylation plays important roles in cellular function and endows protein therapeutics with beneficial properties. However, constructing biosynthetic pathways to study and engineer precise glycan structures on proteins remains a bottleneck. Here, we report a modular, versatile cell-free platform for
glyco
sylation
p
athway assembly by...

Alternative Titles

Full title

A cell-free biosynthesis platform for modular construction of protein glycosylation pathways

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3ed28a4885534b4f9dbe3db52b4d222c

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3ed28a4885534b4f9dbe3db52b4d222c

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-019-12024-9

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