Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia
Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia
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England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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The advanced phases of chronic myeloid leukemia (CML) are known to be more resistant to therapy. This resistance has been associated with the overexpression of ABCB1, which gives rise to the multidrug resistance (MDR) phenomenon. MDR is characterized by resistance to nonrelated drugs, and P-glycoprotein (encoded by ABCB1) has been implicated as the...
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Full title
Wnt/β-catenin pathway regulates ABCB1 transcription in chronic myeloid leukemia
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TN_cdi_doaj_primary_oai_doaj_org_article_3eecff2f371c41e29b9dffa6ea10613d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3eecff2f371c41e29b9dffa6ea10613d
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ISSN
1471-2407
E-ISSN
1471-2407
DOI
10.1186/1471-2407-12-303
