Prime editor‐mediated functional reshaping of ACE2 prevents the entry of multiple human coronaviruse...
Prime editor‐mediated functional reshaping of ACE2 prevents the entry of multiple human coronaviruses, including SARS‐CoV‐2 variants
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Author / Creator
Zhao, Wenwen , Li, Jifang , Wang, Xiao , Xu, Wei , Gao, Bao‐Qing , Xiang, Jiangchao , Hou, Yaofeng , Liu, Wei , Wu, Jing , Qi, Qilian , Wei, Jia , Yang, Xiaoyu , Lu, Lu , Yang, Li , Chen, Jia and Yang, Bei
Publisher
China: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
China: John Wiley & Sons, Inc
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Contents
The spike protein of SARS‐CoV‐2 hijacks the host angiotensin converting enzyme 2 (ACE2) to meditate its entry and is the primary target for vaccine development. Nevertheless, SARS‐CoV‐2 keeps evolving and the latest Omicron subvariants BQ.1 and XBB have gained exceptional immune evasion potential through mutations in their spike proteins, leading t...
Alternative Titles
Full title
Prime editor‐mediated functional reshaping of ACE2 prevents the entry of multiple human coronaviruses, including SARS‐CoV‐2 variants
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_3f1cdc1af3d747359d28a9e3408e69b3
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3f1cdc1af3d747359d28a9e3408e69b3
Other Identifiers
ISSN
2688-2663
E-ISSN
2688-2663
DOI
10.1002/mco2.356
