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Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients

Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3f4646cb0a074c658337fbd49da6c5aa

Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients

About this item

Full title

Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients

Publisher

England: BioMed Central Ltd

Journal title

Acta neuropathologica communications, 2021-02, Vol.9 (1), p.27-27, Article 27

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Brain iron accumulation has been found to accelerate disease progression in amyloid-β(Aβ) positive Alzheimer patients, though the mechanism is still unknown. Microglia have been identified as key players in the disease pathogenesis, and are highly reactive cells responding to aberrations such as increased iron levels. Therefore, using histological...

Alternative Titles

Full title

Iron loading is a prominent feature of activated microglia in Alzheimer's disease patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_3f4646cb0a074c658337fbd49da6c5aa

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3f4646cb0a074c658337fbd49da6c5aa

Other Identifiers

ISSN

2051-5960

E-ISSN

2051-5960

DOI

10.1186/s40478-021-01126-5

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