Azathioprine promotes intestinal epithelial cell differentiation into Paneth cells and alleviates il...
Azathioprine promotes intestinal epithelial cell differentiation into Paneth cells and alleviates ileal Crohn’s disease severity
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Paneth cells (PCs), a subset of intestinal epithelial cells (IECs) found at the base of small intestinal crypts, play an essential role in maintaining intestinal homeostasis. Altered PCs function is associated with diverse intestinal pathologies, including ileal Crohn’s disease (CD). CD patients with ileal involvement have been previously demonstra...
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Full title
Azathioprine promotes intestinal epithelial cell differentiation into Paneth cells and alleviates ileal Crohn’s disease severity
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TN_cdi_doaj_primary_oai_doaj_org_article_3fb83bde6a7b40389c4160db62db9c45
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_3fb83bde6a7b40389c4160db62db9c45
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-63730-4
