Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-C...
Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer: protocol for a phase I, open-label, single-arm, dose-escalation study (REACtiVe-2 trial)
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England: British Medical Journal Publishing Group
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English
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England: British Medical Journal Publishing Group
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IntroductionThe prognosis of patients with advanced pancreatic ductal adenocarcinoma (PDAC) is dismal and conventional chemotherapy treatment delivers limited survival improvement. Immunotherapy may complement our current treatment strategies. We previously demonstrated that the combination of an allogeneic tumour-lysate dendritic cell (DC) vaccine...
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Full title
Safety and tumour-specific immunological responses of combined dendritic cell vaccination and anti-CD40 agonistic antibody treatment for patients with metastatic pancreatic cancer: protocol for a phase I, open-label, single-arm, dose-escalation study (REACtiVe-2 trial)
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TN_cdi_doaj_primary_oai_doaj_org_article_40029583d6574b97bc53298a9b94c429
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_40029583d6574b97bc53298a9b94c429
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ISSN
2044-6055
E-ISSN
2044-6055
DOI
10.1136/bmjopen-2021-060431