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Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_404475003cfa482f8cacf699ff1cb2e9

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

About this item

Full title

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2024-12, Vol.20 (12), p.e1011456

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Inhibitory killer cell immunoglobulin-like receptors (iKIRs) are a family of inhibitory receptors that are expressed by natural killer (NK) cells and late-stage differentiated T cells. There is accumulating evidence that iKIRs regulate T cell-mediated immunity. Recently, we reported that T cell-mediated control was enhanced by iKIRs in chronic vira...

Alternative Titles

Full title

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_404475003cfa482f8cacf699ff1cb2e9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_404475003cfa482f8cacf699ff1cb2e9

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1011456

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