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Synthesis and Anti- Trypanosoma cruzi Activity of New Pyrazole-Thiadiazole Scaffolds

Synthesis and Anti- Trypanosoma cruzi Activity of New Pyrazole-Thiadiazole Scaffolds

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_404ec5fb989244f89628f9043b63ee64

Synthesis and Anti- Trypanosoma cruzi Activity of New Pyrazole-Thiadiazole Scaffolds

About this item

Full title

Synthesis and Anti- Trypanosoma cruzi Activity of New Pyrazole-Thiadiazole Scaffolds

Publisher

Switzerland: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2024-08, Vol.29 (15), p.3544

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Chagas disease, a silent but widespread disease that mainly affects a socioeconomically vulnerable population, lacks innovative safe drug therapy. The available drugs, benznidazole and nifurtimox, are more than fifty years old, have limited efficacy, and carry harmful side effects, highlighting the need for new therapeutics. This study presents two...

Alternative Titles

Full title

Synthesis and Anti- Trypanosoma cruzi Activity of New Pyrazole-Thiadiazole Scaffolds

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_404ec5fb989244f89628f9043b63ee64

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_404ec5fb989244f89628f9043b63ee64

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules29153544

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