Efficient generation of a stable CHO-K1 cell line overexpressing the human water channel aquaporin-5...
Efficient generation of a stable CHO-K1 cell line overexpressing the human water channel aquaporin-5 as tool to generate therapeutic antibodies
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Aquaporins (AQPs) are a family of water permeable channels expressed on the plasma membrane with AQP5 being the major channel expressed in several human tissues including salivary and lacrimal glands. Anti-AQP5 autoantibodies have been observed in patients with Sjögren’s syndrome who are characterised by dryness of both salivary and lacrimal glands...
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Full title
Efficient generation of a stable CHO-K1 cell line overexpressing the human water channel aquaporin-5 as tool to generate therapeutic antibodies
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TN_cdi_doaj_primary_oai_doaj_org_article_409131c0b540484e9187b5e2b8fe2020
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_409131c0b540484e9187b5e2b8fe2020
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-024-67147-x
